Monkeypox outbreak: Tecovirimat or Brincidofovir? Which drug is beneficial?
2 years, 7 months ago

Monkeypox outbreak: Tecovirimat or Brincidofovir? Which drug is beneficial?

Live Mint  

At least one antiviral medicine shows promise against monkeypox and should be investigated further, scientists said as the outbreak widens. The scientists said more work is needed to reach any conclusions but their study found little evidence that another drug, brincidofovir, was beneficial. “Our paper gives a signal that if you had the choice between the two drugs, tecovirimat has shown more promise so far,” Hugh Adler, a researcher at the Liverpool University Hospitals NHS Foundation Trust and lead author, told reporters in a briefing, while urging caution. “We hope that by sharing this data other clinicians who are dealing with cases, particularly if they’re severe cases of monkeypox, might be able to access this drug as well, and that people will have the incentive to do a bigger study.” The cousin of the smallpox virus has spread across Europe and the U.S. in recent days, leading to 131 confirmed cases and another 106 suspected ones across 19 nations, according to the World Health Organization. Brincidofovir didn’t appear to have convincing clinical benefit in three other patients treated with the drug seven days after the initial onset of a rash, researchers said.

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History of this topic

As monkeypox drops in the West, still no vaccines for Africa
2 years, 3 months ago

As monkeypox drops in the West, still no vaccines for Africa

Associated Press  

ABUJA, Nigeria — With monkeypox cases subsiding in Europe and parts of North America, many scientists say now is the time to prioritize stopping the virus in Africa. “Nothing has changed for us here, the focus is all on monkeypox in the West,” said Placide Mbala, a virologist who directs the global health research department at Congo’s Institute of Biomedical …

Texas records first US death from monkeypox
2 years, 3 months ago

Texas records first US death from monkeypox

Daily Mail  

How do you catch monkeypox? Until this worldwide outbreak, monkeypox was usually spread by infected rodents — including rats, mice and even squirrels — in west and central Africa. But when a case is suspected doctors send samples to their local health authorities to be tested for orthopox viruses — the family of viruses that includes monkeypox and smallpox. The …

Penn State University student tests positive for monkeypox
2 years, 4 months ago

Penn State University student tests positive for monkeypox

Daily Mail  

How do you catch monkeypox? Until this worldwide outbreak, monkeypox was usually spread by infected rodents — including rats, mice and even squirrels — in west and central Africa. But when a case is suspected doctors send samples to their local health authorities to be tested for orthopox viruses — the family of viruses that includes monkeypox and smallpox. The …

Monkeypox: Bengaluru doc suggests dos and don'ts
2 years, 4 months ago

Monkeypox: Bengaluru doc suggests dos and don'ts

Hindustan Times  

The Karnataka government is on guard after the state had its first monkeypox scare last week. Hindustan Times spoke to Bengaluru-based Dr Gaurav Sharma, a general physician and cardiologist with over 19 years experience in medical research and new medicine development, about the virus, how to treat it, prevention, symptoms, dos and don'ts, and many more. A) The main difference …

Monkeypox is not COVID, but need to keep a watch, says top scientist
2 years, 4 months ago

Monkeypox is not COVID, but need to keep a watch, says top scientist

The Hindu  

Monkeypox is not COVID kind of virus so there is no need for any alarm over the cases surfacing in different parts of the country. It is also “less infectious, does not spread in the air and only close proximity for a prolonged period, skin to skin contact or exchange of body fluids could lead to the infection,” said Dr. …

'Complete hell': Texas man says monkeypox is '100 times worse' than Covid
2 years, 5 months ago

'Complete hell': Texas man says monkeypox is '100 times worse' than Covid

Daily Mail  

A man in Texas has warned monkeypox was 'complete hell' and '100 times worse than Covid' after catching it — as cases in the United States topped 2,000. Shannahan was administered a monkeypox vaccine after he was diagnosed, but still became bedridden for two days and felt so ill he feared for his life. Luke Shannahan, who lives in Dallas, …

How is monkeypox treated?
2 years, 5 months ago

How is monkeypox treated?

CNN  

CNN — As the monkeypox outbreak continues to grow around the world, many people who have gotten sick with the virus have had mild symptoms and were able to recover without any monkeypox-specific treatment. “The advantages of vaccination are that people who may have been exposed to monkeypox – before the onset of the rash – may benefit from vaccination …

Monkeypox treatments are difficult to get despite the nation's large stockpile
2 years, 5 months ago

Monkeypox treatments are difficult to get despite the nation's large stockpile

NPR  

Monkeypox treatments are difficult to get despite the nation's large stockpile There are enough antiviral pills in the nation's strategic stockpile to treat 1.7 million people with monkeypox. HUANG: Planck is a grad student in New York City studying infectious diseases, and he believes the TPOXX helped him get better faster. HUANG: The FDA and CDC consider TPOXX an investigational …

UK logs 50 new cases of monkeypox; highest after Africa
2 years, 6 months ago

UK logs 50 new cases of monkeypox; highest after Africa

India TV News  

Highlights Most of the monkeypox cases have been identified in gay or bisexual men Globally, more than 30 countries have reported 1,880 infections in countries People exposed to the disease should stay at home and call health services for advice British health officials reported another 50 cases of monkeypox across the country on Friday, for a total of 574 cases. …

Explained | What are the Health Ministry guidelines on monkeypox?
2 years, 6 months ago

Explained | What are the Health Ministry guidelines on monkeypox?

The Hindu  

The story so far: India’s Health Ministry has issued guidelines on the management of monkeypox disease. The 23-page document, available on the Health Ministry website, is an information sheet that lists out the global prevalence of the disease as of May 31, its epidemiology or disease characteristics including the kind of virus that causes the disease, its likely origins, incubation …

How the rhetoric around monkeypox recalls biases in early HIV news coverage
2 years, 6 months ago

How the rhetoric around monkeypox recalls biases in early HIV news coverage

Salon  

The emergence of the monkeypox virus in the United States in the past two weeks has stoked fear of a second pandemic and prompted widespread, often fearful news coverage regarding the unfamiliar virus. "If we learned anything from the early years of HIV, it is that when you say that any particular group is the high-risk group you drive people …

Paying a price: The Hindu Editorial on monkeypox outbreak in Europe
2 years, 6 months ago

Paying a price: The Hindu Editorial on monkeypox outbreak in Europe

The Hindu  

In three weeks since the first case of monkeypox infection was confirmed on May 7 in the U.K. in a person who had just arrived from Nigeria the virus has spread to at least 21 countries and infected 226 people, mainly in Europe and North America. Similarly, the monkeypox genome sequence first shared by Portugal was from a sample collected …

Antiviral drugs may reduce monkeypox symptoms, shorten contagious phase: Study
2 years, 7 months ago

Antiviral drugs may reduce monkeypox symptoms, shorten contagious phase: Study

Hindustan Times  

Some antiviral medications might have the potential to shorten symptoms of monkeypox and reduce the amount of time a patient is contagious, according to a study of seven patients diagnosed with the rare viral disease in the UK between 2018 and 2021. Monkeypox, a close relative of the smallpox virus, is a rare disease classified as a High Consequence Infectious …

Monkeypox isn't like COVID-19 — and that's a good thing
2 years, 7 months ago

Monkeypox isn't like COVID-19 — and that's a good thing

NPR  

Monkeypox isn't like COVID-19 — and that's a good thing Enlarge this image toggle caption Andrew Medichini/AP Andrew Medichini/AP The recent headlines about a sudden emergence of an unusual disease, spreading case by case across countries and continents may, for some, evoke memories of early 2020. Sponsor Message "Let's just say right off the top that monkeypox and COVID are …

EXPLAINED: A Pill You Can Pop At Home To Beat Covid. Here's Why Merck's Antiviral Drug Is Raising Hopes
3 years, 2 months ago

EXPLAINED: A Pill You Can Pop At Home To Beat Covid. Here's Why Merck's Antiviral Drug Is Raising Hopes

News 18  

The global death toll from Covid-19 is said to now have crossed 5 million even as the pandemic’s end is yet to appear within sight. Merck, which has partnered the US-based Ridgeback Biotherapeutics for the development of the drug, said that Phase-3 trials showed that it “significantly reduced the risk of hospitalisation or death… in at risk, non-hospitalised adult patients …

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