Recombinant COVID variants: What is Omicron XE?
Al JazeeraDr Khan on how new ‘hybrid’ sub-variants of COVID form, and what benefits a third dose of the mRNA vaccine provides. This is thought to have been the case in the UK with the discovery of Omicron XE; a recombinant virus made up of the BA.1 and BA.2 sub-variants of Omicron. Update: Memory B cells persist after third COVID vaccine dose More than two years since the pandemic began, COVID-19 still rages on with the arrival of the Omicron variant and its even more infectious sub-variant, BA.2. Now, a new study has shown that the third dose of the mRNA vaccines from Pfizer or Moderna increases the power of these memory B cells that were induced by the second dose of the vaccine by not just strengthening their ability to produce antibodies, but also enabling them to produce antibodies that could help better neutralise mutated versions of the virus such as the Omicron variant. The study states the third dose of the vaccine expands and diversifies the types of memory B cells already present from previous doses, which can respond rapidly and produce antibodies capable of clearing even diversified variants.