Explained | Molnupiravir, Merck’s new drug to treat COVID-19
3 years, 2 months ago

Explained | Molnupiravir, Merck’s new drug to treat COVID-19

The Hindu  

Why is there much excitement about molnupiravir, the investigational new drug for COVID-19? Pharmaceutical major Merck and Ridgeback Biotherapeutics announced via a press release on October 1 the early results from Phase-3 trials that its anti-viral drug molnupiravir halved the chances of hospitalisation in COVID-19 patients with mild or moderate disease. Several noted clinicians have said that these are promising results, and what is particularly encouraging is that molnupiravir is a pill, unlike other drugs — with similar efficacy — used in COVID-19 treatment, which needs to be administered intravenously. The drug has so far been tested only in patients with mild-to-moderate COVID-19, had started treatment within five days of testing positive and had at least one risk factor that increased their risk for severe disease. Another positive factor is that recruitment for the phase-3 trial, that originally envisaged recruiting 1,500 patients for testing the drug’s potency, was halted early by an independent data monitoring committee because the data appeared so encouraging that it would be unethical to delay making the drug more widely available.

History of this topic

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3 years ago
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3 years, 1 month ago
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