Ronald Colman, at right, with Myrna Loy and Alec Francis, fights a Caribbean plague in the 1931 film version of the Sinclair Lewis novel. — David J. Eisenman, University of Maryland “Arrowsmith,” published in 1925, is widely considered Lewis’ most accomplished novel; he was candid with his publisher in considering the book grist for a Nobel Prize. Eisenman writes: “‘You …