Prostate cancer is one of the most common cancers affecting men globally and remains a leading cause of cancer-related deaths worldwide. Two prominent examples include: PARP Inhibitors : These drugs are particularly effective for men with specific genetic mutations in their prostate cancer cells. Radioligand Therapy : This cutting-edge approach involves using radiolabeled molecules to specifically target prostate-specific membrane antigen …
Certain anti-cancer medications also target healthy cells in addition to malignant cells. The mechanism of action of PARP inhibitors, which are specifically used for treating breast and ovarian cancer in individuals with the BRCA gene mutation, has been determined by a team from the University of Geneva in cooperation with Basel-based FoRx Therapeutics. The team observed that both inhibitors kill …
A new genetic test developed at the University of Helsinki and Helsinki University Hospital helps identify ovarian cancer patients who benefit from PARP inhibitors, a type of targeted drug that could be effective against ovarian cancer, the University said in a statement. In recent years, PARP inhibitors have achieved excellent results as a maintenance treatment after surgery and cytostatic therapy …