We have the cause of Alzheimer's all wrong, says neuroscientist
6 years, 9 months ago

We have the cause of Alzheimer's all wrong, says neuroscientist

The Independent  

Sign up to our free Living Well email for advice on living a happier, healthier and longer life Live your life healthier and happier with our free weekly Living Well newsletter Live your life healthier and happier with our free weekly Living Well newsletter SIGN UP I would like to be emailed about offers, events and updates from The Independent. The continued failure of new drugs to make a difference has to be interpreted as evidence that the amyloid protein is not the cause of Alzheimer’s disease. open image in gallery If brains cells don't get enough growth factor, they die When looking at brain tissue taken from deceased Alzheimer’s patients, researchers found that insulin lost its effectiveness as a growth factor, even in people who were not diabetic. Testing these drugs in animal models of another neurodegenerative disorder, Parkinson’s disease, also showed impressive effects, and two clinical trials in Parkinson’s patients showed good protective effects. To see any protective effect in the brain in a clinical trial is completely new, and it supports the new theory that Alzheimer’s and Parkinson’s disease are caused, at least in part, by a lack of growth factor activity in the brain.

History of this topic

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2 years, 4 months ago
Drug that reverses dementia will be wasted without better diagnosis rates, experts warn
2 years, 4 months ago

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