
We have the cause of Alzheimer's all wrong, says neuroscientist
The IndependentSign up to our free Living Well email for advice on living a happier, healthier and longer life Live your life healthier and happier with our free weekly Living Well newsletter Live your life healthier and happier with our free weekly Living Well newsletter SIGN UP I would like to be emailed about offers, events and updates from The Independent. The continued failure of new drugs to make a difference has to be interpreted as evidence that the amyloid protein is not the cause of Alzheimer’s disease. open image in gallery If brains cells don't get enough growth factor, they die When looking at brain tissue taken from deceased Alzheimer’s patients, researchers found that insulin lost its effectiveness as a growth factor, even in people who were not diabetic. Testing these drugs in animal models of another neurodegenerative disorder, Parkinson’s disease, also showed impressive effects, and two clinical trials in Parkinson’s patients showed good protective effects. To see any protective effect in the brain in a clinical trial is completely new, and it supports the new theory that Alzheimer’s and Parkinson’s disease are caused, at least in part, by a lack of growth factor activity in the brain.
History of this topic

Anti-amyloid therapy may keep Alzheimer’s symptoms at bay in certain patients, small study suggests
CNN
The Race to Find a Cure for Alzheimer's
Bloomberg
Why Alzheimer’s scientists are rethinking the amyloid hypothesis
Salon
Alzheimer’s Drugs Eyed by Investors Seeking Obesity-Like Gains
Live Mint
New Alzheimer's drug: only a few eligible for treatment
NL Times
Alzheimer’s wonder drug blocked on NHS over cost
The Telegraph
Researchers investigating if drugs can be repurposed to combat dementia
The Independent
Alzheimer’s breakthrough after drug treatment success
The Independent
How a new pill could stop Alzheimer's disease in its tracks by prompting the brain to 're-wire' itself
Daily Mail
Diabetes drug ‘may lower risk of developing dementia’
The Independent
What are the symptoms and treatments for Alzheimer’s – as new drug is rejected
The Independent
Weight-loss drug ‘could slow progression of Alzheimer’s disease’
The Independent
Alzheimer's drug that can slow disease gets backing from FDA advisers
The Independent
Alzheimer’s drug that can slow disease gets backing from FDA advisers
Associated Press
FDA advisers strongly back new Alzheimer’s drug, despite risks and limitations
NPR
Expected to be a big deal, Alzheimer's drug is pulled after disappointing sales
NPR
Scientists discover there's FIVE types of Alzheimer's and are hopeful breakthrough could lead to cure
Daily Mail
Navigating new Alzheimer's drugs can be confusing and expensive. So do they really help patients?
Salon
A trial to test a new path for preventing Alzheimer’s
The Hindu
Kerala University to create awareness on Alzheimer’s disease among youngsters
The Hindu
A new treatment for Alzheimer’s offers hope—but raises questions, too
Hindustan Times
‘Turning point’ in the fight against Alzheimer’s as drug found to slow disease
The Independent
New drug found to slow Alzheimer’s hailed as turning point
The Independent
Why is this Alzheimer’s breakthrough so important?
The Independent
New Alzheimer’s wonder drug ‘can slow disease progression by 60pc’
The Telegraph
An experimental Alzheimer's drug outperforms one just approved by the FDA
NPR
New drug for Alzheimer's gives hope and ushers in new era in fighting the disease, says doctor
NL Times
Opinion: New Alzheimer’s drugs are costly and controversial. Are we going about this all wrong?
LA Times
Breakthrough Alzheimer’s drugs could be blocked by NHS, campaigners warn
The Telegraph
World ‘on cusp of first generation of treatments for Alzheimer’s’ as new drug ‘slows symptoms’
The Independent
Alzheimer’s drug lowers levels of protein known to cause disease, suggests study
The Independent
Benefits of lecanemab, a new Alzheimer's drug, unclear for patients of color : Short Wave : NPR
NPR
New insights into treatment of Alzheimer's disease: Research
Hindustan Times
EXPLAINER: New drug slows Alzheimer’s but comes with caveats
Associated Press
US approves Alzheimer’s drug that modestly slows disease
Associated Press
U.S. approves Alzheimer’s drug that modestly slows disease
LA Times
FDA approves Alzheimer's drug that appears to modestly slow disease
NPR
Probe: Alzheimer’s drug approval ‘rife with irregularities’
Associated Press
Alzheimer’s drug approval by FDA ‘rife with irregularities,’ probe finds
LA Times
Explained | Will new drug slow progress of Alzheimer’s?
The Hindu
Scientists hail breakthrough as drug proven to slow Alzheimer’s disease
The Independent
Is the new drug lecanemab a breakthrough for Alzheimer’s?
Hindustan Times
Drug slows Alzheimer’s but can it make a real difference?
Associated Press
Alzheimer's drug from Eisai and Biogen slows cognitive decline, side-effects in focus
The Hindu
Breakthrough: A drug slows Alzheimer’s by 5 months, but will it make a big difference?
Firstpost
New Alzheimer’s drug hailed as ‘beginning of the end’ in search for treatment
The Independent
Ground-breaking Alzheimer’s drug may be ‘beginning of the end’ for disease
The Telegraph
New drug appears to slow Alzheimer’s, but can it make a real difference?
LA Times
Study: Alzheimer's drug shows modest success slowing declines in memory, thinking
NPR
Drug that reverses dementia will be wasted without better diagnosis rates, experts warn
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