What triggers our brain to indulge in binge-eating; Research reveals

We are well aware that foods having spiked rates of calories, fats and sugars are detrimental to our health even if their taste is very good. What triggers our brain to indulge in binge-eating; Research reveals The precise neurons that reduce obesity and the mechanism they contain are yet unclear, though, because CRTC1 is found in all brain neurons. To elucidate the mechanism by which CRTC1 suppresses obesity, a research group led by Associate Professor Shigenobu Matsumura from the Graduate School of Human Life and Ecology at Osaka Metropolitan University focused on neurons expressing the melanocortin-4 receptor. Consequently, they created a strain of mice that expresses CRTC1 normally except in MC4R-expressing neurons where it is blocked to examine the effect that losing CRTC1 in those neurons had on obesity and diabetes. "This study has revealed the role that the CRTC1 gene plays in the brain, and part of the mechanism that stops us from overeating high-calorie, fatty, and sugary foods," said Professor Matsumura.